Book Review: Advances in HIV Treatment: HIV Enzyme Inhibitors and Antiretroviral Therapy

HIV/AIDS Therapeutics, Advances in Drug Developments

AIDS (acquired immunodeficiency syndrome) is a deadly human viral infectious disease caused by HIV (human immune-deficient virus) infection. Many AIDS patients before the mid 1990s would lose their life much earlier than expected. After one decade of hard work, antiviral drug cocktails — chiefly the main drivers behind highly active anti-retroviral therapy (HAART) — have been invented for almost all HIV infection treatments. HAART, has proven over the years to prolong the lives of HIV patients. Despite this type of HIV therapy, AIDS is still incurable. HIV patients need to take HAART medications regularly and for life. To find a cure, more revolutionary efforts are indispensable.

To continue HIV/AIDS treatment studies, one must know basic knowledge about HIV/AIDS. Many newcomers in HIV/AIDS research, may be overwhelmed by a flood of information for HIV/AIDS study in animals and humans (interaction between a great diversity effective agents/drugs and a series of different therapeutic targets/mechanisms). This book offers a glimpse into currently licensed anti-HIV drugs and their derivatives for different mechanistic pathways and information — including drug activity levels, mechanisms of action, drug categories, interaction with other drugs, undesired site-effects. HIV-resistance, useful pharmaceutical criteria (ADME), co-treatment (Chapter 1-6) and clinical pharmacogenomic data and information (doses and individuals) (Chapter 7). In addition, some demographic information for HIV infection are introduced (Chapter 8).

This book gives clear explanations and can be easily understood by new researchers in institutes/hospitals and medical students in colleges. It is a good medical book. The reader may find it interesting and educational, making it worth their precious time.

Da-Yong Lu

Shanghai University,

Shanghai, 200444, China


Book Information:

Book Series: Frontiers in HIV Research

Volume: 1

Title: Advances in HIV Treatment: HIV Enzyme Inhibitors and Antiretroviral Therapy

Editors: Gene D. Morse, Sarah Nanzigu

eISBN: 978-1-68108-056-7, 2015
ISBN: 978-1-68108-057-4

Publication year: 2015



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